Structural Biology & Drug Discovery Shared Resource
The Salsbury Group contributes computational biophysics expertise and scientific leadership to the Structural Biology and Drug Discovery Shared Resource of the Atrium Health Wake Forest Baptist Comprehensive Cancer Center. The official resource page is the authoritative source for current leadership, capabilities, and access.
From structural questions to testable models
The Shared Resource connects investigators with complementary expertise in structural biology, computational chemistry, molecular modeling, and medicinal chemistry. Computational work can support projects ranging from basic questions about biomolecular structure and dynamics to structure-guided discovery.
Model
Structure & molecular simulation
Structure preparation, molecular models, force fields, molecular dynamics, and analysis of biomolecular motion and interaction.
Discover
Computational screening
Virtual screening and computational triage that can help prioritize compounds and sharpen experimental questions.
Integrate
Collaborative project design
Consultation that connects computation with structural experiments, biological context, and medicinal chemistry.
Good points to begin a conversation
- A biomolecular structure, interaction, mutation, or mechanism that needs quantitative study
- A structure-based screening or compound-prioritization question
- A grant or pilot project that needs a realistic computational plan
- Existing structural or simulation data that need careful analysis and interpretation
The official Shared Resource page is the authoritative source for current capabilities, access, reservations, and Cancer Center acknowledgment language.
Official Cancer Center resource
Explore capabilities and request access
Review the full service description, resource team, reservation process, and citation guidance on the Wake Forest University School of Medicine website.
Contact the Salsbury Group about computational collaboration